Anxiety & Mood Stabilization Protocol

Protocol Overview

Selank is a synthetic peptide developed in Russia as an anxiolytic (anti-anxiety) agent. Unlike benzodiazepines, it reduces anxiety without sedation, cognitive impairment, or addiction potential. This protocol addresses generalized anxiety, social anxiety, stress-related symptoms, and mood instability.

Benefits

• Reduced anxiety without sedation
• Improved mood and emotional stability
• Better stress resilience
• Enhanced cognitive function
• No addiction or withdrawal
• Immune system support

Who This Is For

• Generalized anxiety disorder
• Social anxiety
• Stress-related symptoms
• Mood instability
• Those seeking alternatives to benzodiazepines

How Selank Works for Anxiety

Mechanisms of Action

• GABA modulation: Enhances GABAergic neurotransmission without direct GABA receptor binding
• Serotonin regulation: Normalizes serotonin levels in anxiety-related brain regions
• Enkephalin metabolism: Modulates endogenous opioid peptides
• BDNF increase: Promotes neuroplasticity and stress resilience
• Stress hormone regulation: Normalizes cortisol and other stress markers

Advantages Over Traditional Anxiolytics

• No sedation or cognitive impairment
• No addiction potential
• No withdrawal symptoms
• Enhances rather than impairs cognition
• Supports immune function
• Can be used long-term

Dosing Protocol

Standard Dosing

Dose: 250-500 mcg per day

Administration: Intranasal spray

Frequency: 1-2 times daily

Dosing Schedule Options:

Option A: Once Daily

• 250-500 mcg in the morning
• Provides all-day anxiety relief
• Best for generalized anxiety

Option B: Twice Daily

• 250 mcg morning + 250 mcg afternoon
• More consistent anxiety control
• Best for severe or persistent anxiety

Option C: As-Needed

• 250-500 mcg before anxiety-provoking situations
• Social events, presentations, etc.
• Takes effect within 15-30 minutes

Protocol Duration

• Acute anxiety: 4-6 weeks
• Chronic anxiety: 8-12 weeks
• Maintenance: Can continue long-term with breaks
• Cycling: 8 weeks on, 2-4 weeks off

Expected Results Timeline

Day 1: Immediate Effects

• Reduced anxiety within 15-30 minutes
• Calmer mental state
• Improved mood
• No sedation or impairment

Week 1: Acute Benefits

• Consistent anxiety reduction
• Better stress management
• Improved sleep quality
• Enhanced social confidence

Weeks 2-4: Sustained Improvement

• 40-60% reduction in anxiety symptoms
• More stable mood
• Better emotional regulation
• Reduced physical anxiety symptoms

Weeks 4-8: Long-term Benefits

• 60-80% symptom improvement
• Increased stress resilience
• Better quality of life
• Sustained benefits with continued use

Complementary Interventions

Therapy Integration

• CBT (Cognitive Behavioral Therapy): Addresses thought patterns
• Mindfulness meditation: 10-20 minutes daily
• Exposure therapy: For specific phobias
• Breathing exercises: Box breathing, 4-7-8 technique

Lifestyle Modifications

• Regular exercise: 30 minutes daily reduces anxiety
• Sleep hygiene: 7-9 hours consistent schedule
• Caffeine reduction: Limit to morning only
• Alcohol avoidance: Worsens anxiety long-term

Supplements

• Magnesium glycinate: 400mg before bed
• L-theanine: 200mg as needed
• Ashwagandha: 600mg daily
• Omega-3s: 2-4g EPA+DHA daily

Safety and Monitoring

Side Effects

• Generally very well tolerated
• Mild drowsiness (rare)
• Nasal irritation from spray
• Headache (uncommon)

When to Seek Professional Help

• Suicidal thoughts
• Panic attacks
• Severe anxiety interfering with daily life
• No improvement after 4 weeks
• Worsening symptoms

Cost Analysis

• Selank (0.15% solution, 3ml): $40-80 per bottle
• 8-week protocol: $80-160 total
• Cost per day: $1.50-3.00
• Significantly less than prescription anxiolytics