How Is BPC-157 Made?
Synthesis and production methods
Solid-Phase Peptide Synthesis
BPC-157 is manufactured through solid-phase peptide synthesis (SPPS), the standard method for producing peptides in laboratories. This process builds the peptide chain one amino acid at a time on a solid support.
The SPPS Process
- Amino acids are added sequentially to build the 15-amino acid chain
- Each addition is carefully controlled and verified
- The completed peptide is cleaved from the solid support
- Purification removes any incomplete or incorrect sequences
Quality Control
Proper manufacturing includes rigorous quality control:
- Purity Testing: HPLC analysis to verify composition
- Mass Spectrometry: Confirms molecular weight
- Sterility Testing: Ensures no bacterial contamination
- Endotoxin Testing: Checks for harmful bacterial byproducts