Ipamorelin Dosing Guide

Why Ipamorelin is Popular

Advantages Over Other GHRPs

• Selective GH Release: Minimal effects on cortisol and prolactin (unlike GHRP-2/6)
• No Hunger Increase: Doesn't significantly increase appetite (unlike GHRP-6)
• Clean Side Effect Profile: Fewer side effects than other GHRPs
• Flexible Dosing: Wide effective dose range (100-300 mcg)
• Excellent for Stacking: Synergizes perfectly with CJC-1295

Comparison to Other GHRPs

• vs GHRP-2: Ipamorelin has less cortisol/prolactin elevation, cleaner profile
• vs GHRP-6: Ipamorelin doesn't increase hunger, better for fat loss
• vs Hexarelin: Ipamorelin has less desensitization, safer long-term

Ipamorelin Dosing Calculator

Use this calculator to determine your personalized Ipamorelin dose based on body weight and goals:

Standard Dosing Protocols

Ipamorelin Monotherapy

Typical Dose: 200-300 mcg per injection

Frequency: 2-3 times daily

Timing:

• Morning: Upon waking (empty stomach)
• Post-workout: Immediately after training (if 3x daily)
• Before bed: 30-60 minutes before sleep (most important dose)

Duration: 8-12 weeks, then 4-week break

Ipamorelin + CJC-1295 Stack (Most Popular)

Ipamorelin: 200-300 mcg per dose

CJC-1295 (no DAC): 100-200 mcg per dose

Frequency: 2-3 times daily, dosed together

Timing: Same as monotherapy

Duration: 12 weeks on, 4 weeks off

Synergy: Combined GH release is 3-5x greater than either alone

Goal-Specific Protocols

Administration Guidelines

Reconstitution

1. Vial Size: Typically 5mg (5000 mcg)
2. Bacteriostatic Water: Add 2ml for 2500 mcg/ml concentration
3. Mixing: Inject water slowly down side of vial, swirl gently (don't shake)
4. Storage: Refrigerate immediately, use within 30 days
5. Calculation: 2500 mcg/ml means 0.1ml (10 units) = 250 mcg

Injection Technique

1. Site: Subcutaneous in abdomen or thigh (rotate sites)
2. Needle: Insulin syringe (29-31 gauge, 0.5-1ml)
3. Technique: Pinch skin, insert at 45° angle, inject slowly
4. After Injection: Apply gentle pressure, don't massage

Timing Optimization

• Empty Stomach: Wait 15-20 minutes before eating after injection
• Avoid High Blood Sugar: Don't inject immediately after meals (blunts GH release)
• Consistency: Same times each day for best results
• Before Bed Dose: Most important for GH release during sleep
• Post-Workout: Excellent timing for muscle growth and recovery

Stacking Administration

When stacking Ipamorelin with CJC-1295:

• Draw both peptides into same syringe (or use separate syringes)
• Inject at same time (can be same injection site or different sites)
• Wait 15-20 minutes before eating
• Synergistic effect occurs within 30-60 minutes

Expected Results Timeline

Week-by-Week Progression

• Week 1-2: Improved sleep quality, deeper sleep, vivid dreams
• Week 2-3: Enhanced recovery, reduced muscle soreness
• Week 3-4: Improved skin quality, better hydration
• Week 4-6: Noticeable fat loss (especially abdominal), increased energy
• Week 6-8: Visible muscle gains, improved strength
• Week 8-12: Significant body composition changes, optimal benefits

Measurable Outcomes

• Body Composition: 2-4 kg lean mass gain, 2-5% body fat reduction
• Performance: 10-15% strength increase, improved endurance
• Recovery: 30-50% faster recovery between workouts
• Sleep: Increased deep sleep and REM sleep
• Skin: Improved elasticity, reduced fine lines
• Energy: Sustained energy throughout day

Safety and Side Effects

Common Side Effects (Minimal with Ipamorelin)

• Water Retention: Mild, temporary (first 1-2 weeks)
• Injection Site Reactions: Redness, mild swelling (5-10% of users)
• Headache: Occasional, usually mild (5% of users)
• Flushing: Temporary facial flushing post-injection (rare)

What Ipamorelin DOESN'T Cause (vs Other GHRPs)

• No Increased Hunger: Unlike GHRP-6 (major advantage for fat loss)
• No Cortisol Spike: Unlike GHRP-2 (cleaner profile)
• No Prolactin Increase: Unlike GHRP-2/6 (no gynecomastia risk)
• Minimal Desensitization: Unlike Hexarelin (safer long-term)

Contraindications

• Active cancer or history of cancer
• Diabetic retinopathy
• Pregnancy or breastfeeding
• Uncontrolled diabetes

Monitoring

• Baseline: IGF-1 levels, fasting glucose, HbA1c
• Follow-up: Repeat labs at 8-12 weeks
• Track: Body composition, sleep quality, recovery, energy

Cycling and Long-Term Use

Standard Cycling

• On Cycle: 8-12 weeks
• Off Cycle: 4 weeks minimum
• Rationale: Prevents receptor desensitization, maintains effectiveness

Long-Term Anti-Aging Use

• Protocol: 8 weeks on, 2 weeks off (repeat indefinitely)
• Dose: Lower doses (200 mcg, 2x daily)
• Monitoring: Regular lab work every 6 months

Blast and Cruise

• Blast: 12 weeks at higher doses (300 mcg, 3x daily)
• Cruise: 8-12 weeks at lower doses (200 mcg, 2x daily)
• Benefits: Maintains some benefits year-round while preventing desensitization

Cost Analysis

Ipamorelin Monotherapy

• 5mg Vial: $25-45
• Monthly Cost (2x daily): $75-135
• Monthly Cost (3x daily): $110-200
• 12-Week Protocol: $225-600

Ipamorelin + CJC-1295 Stack

• Monthly Cost: $150-250 combined
• 12-Week Protocol: $450-750
• Value: Best results per dollar (synergistic effects)

Cost-Saving Tips

• Buy in bulk (3-6 month supply) for discounts
• Start with 2x daily dosing (morning/bed) before adding 3rd dose
• Use lower doses for anti-aging vs muscle building
• Stack with CJC-1295 for maximum value (synergy)

Troubleshooting

Not Seeing Results After 4 Weeks?

• Increase dose by 50-100 mcg per injection
• Add 3rd daily dose if only doing 2x daily
• Stack with CJC-1295 if not already
• Verify peptide quality (should be >98% purity)
• Check timing (empty stomach, proper spacing)
• Ensure adequate sleep (GH release occurs during deep sleep)

Water Retention?

• Usually resolves after 2-3 weeks
• Reduce sodium intake
• Increase water consumption (paradoxically helps)
• Consider reducing dose temporarily

Headaches?

• Reduce dose by 25-50%
• Ensure adequate hydration
• Usually resolves after first week
• Take with food if persistent (though less optimal)

Related Resources

• Ipamorelin Overview
• CJC-1295 (Stacking Partner)
• CJC-1295 Dosing Guide
• Muscle Building Protocol
• Body Recomposition Protocol